Parkinson’s is often thought of as a condition that affects everyone the same way, but research is beginning to highlight key differences in how the disease presents and progresses in women compared to men. Historically, most Parkinson’s research has focused on men, meaning that many of the unique challenges women face have been understudied and overlooked.

As awareness grows, it’s important for women with Parkinson’s, their families, and caregivers to understand how symptoms, treatment responses, and overall experiences may differ—and why more research is needed to ensure better, tailored care for women living with the condition.

Do Women Experience Parkinson’s Differently?

Yes! Studies suggest that biological, hormonal, and social factors can all contribute to differences in how Parkinson’s affects women. Some key differences include:

Later Diagnosis – On average, women tend to be diagnosed later than men, possibly due to differences in symptoms or the fact that Parkinson’s is often misdiagnosed as anxiety or menopause-related changes.

Different Medication Responses – Women often experience more side effects from Parkinson’s medications, particularly dyskinesia (involuntary movements), due to differences in body composition and metabolism.

More Non-Motor Symptoms – Women are more likely to experience anxiety, depression, fatigue, and sleep disturbances—symptoms that are often overlooked but can have a major impact on quality of life.

Hormonal Influence – Estrogen appears to play a protective role in dopamine regulation, meaning that hormonal changes during menstruation, pregnancy, and menopause can worsen symptoms or impact medication effectiveness.

Caregiving & Social Expectations – Women with Parkinson’s are more likely to be caregivers themselves, meaning they may delay seeking help for their own symptoms while caring for a spouse, parent, or children.

Why Are These Differences Important?

Most clinical trials and treatments for Parkinson’s have been developed based on studies that predominantly included men. This means that medication dosages, symptom management strategies, and even diagnostic criteria may not be fully optimised for women.

Raising awareness of how Parkinson’s affects women differently can lead to:

·         More inclusive research to improve treatments tailored to women’s needs.

·         Better medication management to address unique responses and side effects.

·         More support for women navigating caregiving responsibilities while managing their own condition.

How Can Women with Parkinson’s Get the Right Support?

If you or a loved one is a woman living with Parkinson’s, advocating for personalised care and finding a support network can make a huge difference. Here’s what can help:

Work with a Specialist – A neurologist who understands the unique challenges women face with Parkinson’s can help tailor treatment plans to individual needs.

Track Symptoms & Medication Effects – Keeping a journal of symptom changes during hormonal cycles, pregnancy, or menopause can help identify patterns and guide treatment adjustments.

Join a Support Community – Finding others who understand what you’re going through can be invaluable.